Meersseman W, Lagrou K, Sciot R, de Jonckheere J, Haberler C, Walochnik J, Peetermans WE, van Wijngaerden E Rapidly fatal Acanthamoeba encephalitis and treatment of cryoglobulinemia. [Journal Article] Emerg Infect Dis 2007 Mar; 13(3):469-71.
We describe a 66-year-old woman with therapy-refractory cryoglobulinemia treated with rituximab, plasmapheresis, and steroids; a case of fatal meningoencephalitis caused by Acanthamoeba spp. then developed. Such infections are rare and show an unusually rapid course (possibly related to rituximab).
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