| Title | Methaemoglobinaemia caused by hydroxycarbamide (hydroxyurea) ingestion in a dog. | | Author(s) | Wray JD | | Institution | Centre for Small Animal Studies, Animal Health Trust, Lanwades Park, Kentford, Newmarket. Suffolk CB8 7UU, UK. | | Source | J Small Anim Pract 2007 Sep 7. | | Abstract | A three-year-old female neutered greyhound was presented after ingestion of its owner's hydroxycarbamide (hydroxyurea) tablets. The dog was found to be cyanosed, and methaemoglobinaemia was demonstrated by co-oximetry. Therapy included methylene blue, oxygen, packed red blood cell transfusion, N-acetylcysteine and crystalloid fluids. Methaemoglobinaemia resolved within 16 hours. Granulocyte colony-stimulating factor was administered for five days in an attempt to prevent severe neutropenia. Mild delayed transient myelotoxicity was suspected. The dog made a full recovery. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 17850274 |
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