Murray DJ, Vesely MJ, Novak CB, Irish J, Crump M, Neligan PC
Bisphosphonates and avascular necrosis of the mandible: Case report and review of the literature. [Journal Article]
J Plast Reconstr Aesthet Surg 2008; 61(1):94-8.
BACKGROUND: Avascular necrosis of the mandible or maxilla is being recognized with increasing frequency in patients who are being treated with bisphosphonates for metastatic cancers.
METHODS AND RESULTS: A patient who was treated for avascular necrosis following treatment with bisphosphonates for multiple myeloma is presented.
CONCLUSION: Prophylactic and preventative measures should be instituted prior to commencing treatment with bisphosphonates to minimize the risk of developing avascular necrosis.
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