| Title | Typical and atypical pulmonary carcinoids: our institutional experience. | | Author(s) | Bini A, Brandolini J, Cassanelli N, Davoli F, Dolci G, Sellitri F, Stella F | | Institution | University of Bologna, Italy. | | Source | Interact Cardiovasc Thorac Surg 2008 Mar 18. | | Abstract | Pulmonary carcinoids are rare malignant neoplasms, accounting for 2-5% of all lung tumors, with an approximate annual incidence of 2.3-2.8 cases per million of the population. We relate our experience of 54 patients (21 M, 33 F, mean age 53+/-15 years) treated between July 1986 and April 2006. All the patients underwent preoperative fibrobronchoscopy: preoperative diagnosis was made in 28 patients (52%). Surgical treatment consisted in: 31 standard lobectomies, 6 pneumonectomies, 5 bilobectomies, 2 sleeve lobectomies, 2 anatomic segmentectomies, 6 wedge resections; two patients were managed with sleeve bronchial procedure of the left main bronchus without lung resection. Fifty-four patients were followed with a mean time of observation of 67 months: 6 (11%) deaths occurred, at a mean period of 49 months after surgery; there were no postoperative deaths. Overall, 5-year survival was 91%, 10-years 83%: 5-year survival was 91% for typical carcoinoids (TC) versus 88% for atypical (AC), 10-years 91% for TC and 44% for AC (significant value, p=0.0487). Carcinoid tumors are a distinct group of neuroendocrine tumors with a good prognosis in most cases. Surgery currently represents the best treatment with good results at mid- and long-term survival, according to an acceptable risk. Keywords: Pulmonary carcinoid; Neuroendocrine; Diagnosis; Treatment. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18349148 |
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