| Title | Congenital Langerhans Cell Histiocytosis Mimicking a "Blueberry Muffin Baby" | | Author(s) | Sankilampi U, Huikko-Tarvainen S, Kärjä V, Pirinen E, Naukkarinen A, Hollmén A | | Institution | Departments of *Pediatrics †Dermatology ‡Pathology, Kuopio University Hospital, Kuopio, Finland. | | Source | J Pediatr Hematol Oncol 2008 Mar; 30(3):245-248. | | Abstract | Congenital Langerhans cell histiocytosis (LCH) is a rare condition with great diversity. A case of congenital skin-only LCH presenting as a "blueberry muffin baby" with a spontaneous regression by the age of 8 months is reported here. New insights into clinical manifestations and prognosis, which is not uniformly positive, are discussed. A thorough examination and a careful follow-up should be provided to these patients. Systemic therapy is warranted in multi-system disease; no consensus on treatment exists in case of LCH isolated to skin. The diagnosis of congenital self-healing LCH should be made only retrospectively. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18376291 |
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