| Title | Giant hepatic adenoma with atypical features in a patient on oxcarbazepine therapy. | | Author(s) | Lautz TB, Finegold MJ, Chin AC, Superina RA | | Institution | Department of Surgery, Children's Memorial Hospital, Feinberg School of Medicine of Northwestern University, Chicago, IL 60614, USA. | | Source | J Pediatr Surg 2008 Apr; 43(4):751-4. | | Abstract | An association between oxcarbazepine therapy and hepatic adenoma (HA) has been documented in animal models but not observed in humans. The authors report a case of a 16-year-old girl on oxcarbazepine therapy for seizure disorder who presented with a giant HA. Pathology of the HA was notable for marked periductal fibrosis and glycoprotein inclusions in the nontumor liver. The patient was not on oral contraceptives and has no other known risk factors for HA. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18405728 |
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