| Title | Plasma exchange in a case of severe factor x deficiency in pregnancy: critical review of the literature. | | Author(s) | Chiossi G, Spero JA, Esaka EJ, Novic K, Celebrezze JU, Golde SH, Thomas RL | | Institution | Department of Obstetrics and Gynecology, Division of Maternal and Fetal Medicine, Allegheny General Hospital, Pittsburgh, Pennsylvania. | | Source | Am J Perinatol 2008 Mar; 25(3):189-92. | | Abstract | Hereditary factor X deficiency represents an uncommon challenge in pregnancy. A 30-year-old primigravida affected by severe factor X deficiency was followed from 6 weeks of gestation until delivery. Factor X was provided prior to delivery for the first time in pregnancy via plasma exchange. The pregnancy and postpartum period were not complicated by bleeding episodes; therefore this approach was accompanied by lower cost and fewer side effects when compared with fresh-frozen plasma and prothrombin complex concentrates infusion, two therapeutic options already used in pregnancy. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18425721 |
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