Addison's disease, diffuse skin, and mucosal hyperpigmenation with subtle "flu-like" symptoms--a report of two cases. Pediatric dermatology [Pediatr Dermatol] Journal article | | Title | Addison's disease, diffuse skin, and mucosal hyperpigmenation with subtle "flu-like" symptoms--a report of two cases. | | Author(s) | Burk CJ, Ciocca G, Heath CR, Duarte A, Dohil M, Connelly EA | | Institution | Department of Dermatology and Cutaneous Surgery, Division of Pediatric Dermatology, University of Miami, Miller School of Medicine, Miami, Florida, USA. cynthiajburk@yahoo.com | | Source | Pediatr Dermatol 2008 Mar-Apr; 25(2):215-8. | | Abstract | Addison's disease, or chronic adrenocortical insufficiency, is the overproduction of adrenocorticotropic hormone by the pituitary gland as a compensatory mechanism for decreased cortisol production by the adrenal glands. Classically, patients affected with Addison's disease develop weakness, anorexia, electrolyte imbalances: decreased sodium and chloride with increased serum potassium resulting in hypotension, and hyperpigmentation of the skin and mucous membranes. Herein this case report, we focus on the subtle findings of diffuse hyperpigmentation and intermittent but repetitive "flu-like" symptoms in two patients to correctly identify the diagnosis of Addison's disease effectively and efficiently. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18429783 |
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