Walker JL, Smith GH, Gaston MS, Robinson CM
Spontaneous compartment syndrome in association with simvastatin-induced myositis. [Journal Article]
Emerg Med J 2008 May; 25(5):305-6.
Compartment syndrome as a result of simvastatin-induced myositis is extremely rare. This case discusses a patient with spontaneous onset compartment syndrome that necessitated four-compartment fasciotomy. A thorough investigation into its cause highlighted statin-induced myositis as the most likely aetiological agent. When investigating a patient with unexplained spontaneous compartment syndrome it is important to consider drug-induced myositis. This case reinforces the difficulty faced in diagnosing spontaneous compartment syndrome.
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