| Title | Pubertal adiposity after fetal growth restraint: toward a calorie restriction mimetic approach. | | Author(s) | Ibáñez L, López-Bermejo A, de Zegher F | | Institution | Endocrinology Unit, Hospital Sant Joan de Déu, University of Barcelona, 08950 Esplugues, Barcelona, Spain. | | Source | Metabolism 2008 May; 57(5):672-5. | | Abstract | Randomized studies in early-maturing (P2 <8 years, B2 between 8 and 9 years), low-birth weight girls (N = 60) show that calorie restriction mimetic therapy with metformin for 3 years is accompanied by a strikingly leaner body composition (on average, 5.2 kg less gain of fat; 1.6 kg more gain of lean mass; P < .0001). | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18442632 |
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