| Title | Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia. | | Author(s) | Wilde AA, Bhuiyan ZA, Crotti L, Facchini M, De Ferrari GM, Paul T, Ferrandi C, Koolbergen DR, Odero A, Schwartz PJ | | Institution | University of Amsterdam, Amsterdam. a.a.wilde@amc.uva.nl | | Source | N Engl J Med 2008 May 8; 358(19):2024-9. | | MeSH | Adolescent
Catecholamines
Defibrillators, Implantable
Electrocardiography
Female
Follow-Up Studies
Heart
Humans
Male
Sympathectomy
Tachycardia, Ventricular
| | Abstract | Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. Beta-blockers are the cornerstone of therapy, but some patients do not have a complete response to this therapy and receive an implantable cardioverter-defibrillator (ICD). Given the nature of catecholaminergic polymorphic ventricular tachycardia, ICD shocks may trigger new arrhythmias, leading to the administration of multiple shocks. We describe the long-term efficacy of surgical left cardiac sympathetic denervation in three young adults with catecholaminergic polymorphic ventricular tachycardia, all of whom had symptoms before the procedure and were symptom-free afterward. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 18463378 |
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