| Title | Evolution of Brunner gland hamartoma associated with Helicobacter pylori infection. | | Author(s) | Kurella RR, Ancha HR, Hussain S, Lightfoot SA, Harty R | | Institution | Division of Gastroenterology, Department of Medicine, Oklahoma University Health Sciences Center, Oklahoma City, OK, USA. | | Source | South Med J 2008 Jun; 101(6):648-50. | | Abstract | The pathogenesis of Brunner gland hamartoma of the duodenum is unknown. This case report describes the chronology of the development of Brunner gland hamartoma from Brunner gland hyperplasia over a 12-year interval. The study subject, a 64-year-old man with chronic iron deficiency anemia, underwent serial upper endoscopies during this period. Repeated endoscopies demonstrated the evolution of Brunner gland hyperplasia, as manifest endoscopically by a submucosal mass, to a pedunculated polyp with histologic features of Brunner gland hamartoma. The duodenal polypoid mass was removed by snare polypectomy. The patient also had a chronic Helicobacter pylori infection of the stomach. This report details the time-dependent evolution of Brunner gland hyperplasia to hamartoma in association with chronic gastric H. pylori infection. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18475238 |
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