Examining Dentinal Carious Lesions as a Predisposing Factor for the Oral Prevalence of Candida spp in HIV-infected Children. Journal of dentistry for children (Chicago, Ill.) [J Dent Child (Chic)] Journal article | | Title | Examining Dentinal Carious Lesions as a Predisposing Factor for the Oral Prevalence of Candida spp in HIV-infected Children. | | Author(s) | Cerqueira DF, Portela MB, Pomarico L, de Araújo Soares RG, de Souza IP, Castro GF | | Institution | Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. daniellefc@terra.com.br. | | Source | J Dent Child (Chic) 2007 May-Aug; 74(2):98-103. | | Abstract | PURPOSE: The aims of this study were to verify the oral prevalence of Candida spp in HIV-infected children, and investigate the association between Candida colonization and dentinal caries lesions.
METHODS: Whole stimulated saliva was collected from 62 HIV-infected children (group 1) and 40 seronegative siblings (group 2), followed by oral examination to determine: dmft/dmfs scores, DMFT/DMFS scores, the number of dentinal carious teeth (D+) and the presence of oral candidiasis. The salivary samples were cultured, and plates with positive isolation (G+) were classified as mild growth, moderate growth, and strong growth. Data was analyzed using chi-square, Mann-Whitney, and Spearman tests for correlations.
RESULTS: The patients' mean age was 8.8 for group 1 and 8.0 years for group 2. In group 1, 61% of the subjects had AIDS. Eighty percent of HIV-infected children (N=50) were positive for Candida growth, having a mean CD4% of 22, those who were Candida-free (N=12) presented a mean CD4% of 21. Correlation was observed between the mean D+ and G+ in groups 1 and 2 (P<.05, Mann-Whitney test), but not between the mean dmft/dmfs-DMFT/DMFS in group 1 (P>.05, Mann-Whitney test). Association of G+ and the D+ was noted in group 1 (P<.05; chi-square test). Positive correlation between high Candida counts and an increase in D+ was demonstrated in groups 1 and 2 (P<.05).
CONCLUSIONS: Dentinal carious lesions may be associated with Candida spp colonization in HIV-infected children. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18477427 |
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