Hino N, Ikushima Y, Tsuyuguchi M, Sohnaka Y, Wada D, Yamasaki S, Miyake H, Ogasawara T, Yamamoto Y, Ohura R [A Case of Occult Breast Cancer Successfully Treated by Capecitabine in Combination with Weekly Paclitaxel Followed by FEC(75).] [English Abstract, Journal Article] Gan To Kagaku Ryoho 2008 May; 35(5):809-12.
A 78-year-old woman was referred to our hospital complaining of a hard nodule on the left side of her neck. Histological examination of this nodule showed metastatic carcinoma from breast cancer. Further examination revealed paraaortic lymphnode swelling and no breast tumors. We diagnosed her tumors as occult breast cancer and its metastasis to lymphnodes(cT0N3cM1, Stage IV). We used weekly paclitaxel followed by a FEC75 regimen. The neck nodule size did not change after administration twice. We added capecitabine to the weekly paclitaxel, which had decreased the size of the nodule immediately. After this chemotherapy, PET-CT revealed that the lymphnode metastasis had disappeared completely. It was considered that the addition of capecitabine in the early phase of the regimen was useful for this case.
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