| Title | Vascular thrombosis associated with antiphospholipide syndrome. | | Author(s) | Glasnović M, Bosnjak I, Vcev A, Soldo I, Bedeković D, Milaković S, Hecimović V, Horvatić E, Bardek M | | Institution | Department of Internal Medicine, School of Medicine, University J. J. Strossmayer, Osijek, Croatia. glasnovic.marija@kbo.hr | | Source | Coll Antropol 2008 Mar; 32(1):103-7. | | Abstract | The aim of this study was to present our diagnostic and therapeutic experience with antiphospholipide syndrome (APS) and vascular thrombosis. Ninety-nine patients with positive antiphospholipide antibodies (aPL) and vascular thrombosis were included in the study: forty patients, according to clinical classification criteria, had primary antiphospholipide syndrome (PAPS), and fifty-nine patients had secondary antiphospholipide syndrome (SAPS). In PAPS group, 82.5% of the patients were LA-positive, 37.5% of the patients were IgG aCL-positive, 27.5% of the patients were IgM aCL-positive, and 15% of the patients were IgG antibeta2GPI-positive. In SAPS group, 61% of the patients were LA-positive, 50.8% of the patients were IgG aCL-positive, and 47.5% of the patients were IgM aCL-positive. Administered therapy was low molecular weight heparin (LMWH) throughout 7 days, followed by warfarin with prothrombin time maintained between 2.0 and 3.0 INR. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18494194 |
|
