| Title | Spherical amyloid deposition in a prolactin-producing pituitary adenoma. | | Author(s) | Gul S, Bahadir B, Dusak A, Kalayci M, Edebali N, Acikgoz B | | Institution | Department of Neurosurgery, Zonguldak Karaelmas University Medical School, Zonguldak, Turkey. | | Source | Neuropathology 2008 May 21. | | Abstract | A 41-year-old man presented with headache, right-sided ophthalmic pain and visual deficit. His neurological examination was normal except for bitemporal hemianopsia and right lower quadranopsia. MRI demonstrated a mass arising from the pituitary gland. Hormonal analysis revealed an elevated prolactin level of 4700 ng/mL (normal 4.04-15.2 ng/mL). MRI revealed hypointense signal on T2-weighted images. Moreover, we also concluded that foci with no intravenous contrast enhancement represent the amyloid deposits. The patient underwent trans-sphenoidal resection of the pituitary adenoma. Histological examination revealed an adenoma with spheroid amyloid deposits adjacent to prolactin-staining adenoma cells. The patient recovered from the surgery without complications. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18498287 |
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