Weis S, Llenos IC
Primary leptomeningeal B-cell lymphoma of MALT-type in statu nascendi: A case report and review of the literature. [JOURNAL ARTICLE]
Clin Neurol Neurosurg 2008 May 20.
A 29-year-old Caucasian female suffering from bipolar disorder, mixed, moderate with psychotic features (DSM-IV 296.64) and panic disorder without agoraphobia (DSM-IV 300.01) died as a result of an accidental overdose. Upon histopathological examination of the brain, as an incidental finding, a small lesion (1mmx2mm) composed of heterogeneous small lymphocytic cells (CD20-positive) including centrocyte-like cells, a few small lymphocytes and rare immunoblast-like cells was evident. The diagnosis of primary leptomeningeal MALT-type lymphoma was made. Due to its small size and lack of space-occupying characteristics, the lesion is considered to be in statu nascendi. This case adds another aspect to the rare entity of primary leptomeningeal lymphomas.
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