| Title | Beneficial effects of Lagenaria siceraria (Mol.) Standley fruit epicarp in animal models. | | Author(s) | Deshpande JR, Choudhari AA, Mishra MR, Meghre VS, Wadodkar SG, Dorle AK | | Institution | Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Amravati Road, Nagpur 440 010, India. jitendra_despande@rediffmail.com | | Source | Indian J Exp Biol 2008 Apr; 46(4):234-42. | | Abstract | Lagenaria siceraria (Mol.) Standley fruit (bottle gourd), a commonly used vegetable in India is described as cardiotonic and as a general tonic in Ayurveda. Keeping in view the presence of free radical scavenging activity in L. siceraria and involvement of free radicals in the development of various disorders, present studies were designed to evaluate the ethanolic extract of L. siceraria fruit against the disorders where free radicals play a major role in pathogenesis. The extract was found effective as hepatoprotective, antioxidant, antihyperglycemic, immunomodulatory, antihyperlipidemic and cardiotonic agent. The results showed that the radical scavenging capacity of L. siceraria fruit may be responsible for various biological activities studied. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18512332 |
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