Jin J, Lee YS, Jeong SW, Jeong JH, Lee SH, Tae K Change of acoustic parameters before and after treatment in laryngopharyngeal reflux patients. [Journal Article] Laryngoscope 2008 May; 118(5):938-41.
OBJECTIVES: To evaluate the usefulness of acoustic parameters as an indicator of laryngopharyngeal reflux (LPR) treatment efficacy. STUDY DESIGN: A prospective case series analysis. MATERIALS AND METHODS: From January to September 2005, we prospectively analyzed 40 patients who were diagnosed with laryngopharyngeal reflux by 24-hour ambulatory double-probe pH monitoring. Laryngopharyngeal reflux patients were treated medically and voice analysis was conducted three times: before treatment, 1 to 2 months after treatment, and 3 to 4 months after treatment. Jitter, shimmer, and harmonic-to-noise ratio (HNR) were analyzed as the acoustic parameters. Pre- and posttreatment reflux symptom index and reflux finding score were documented. RESULTS: Jitter, shimmer, and HNR had improved significantly at 1 to 2 months after treatment and were maintained at 3 to 4 months after treatment. Jitter was significantly correlated with reflux symptom index. CONCLUSION: Acoustic parameters can be used as indicators of treatment efficacy for laryngopharyngeal reflux disease.
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