Management of femoral fracture in a patient with essential thrombocythemia treated with plateletpheresis and intramedullary rod fixation, followed by hydroxyurea: a case report. The American journal of emergency medicine [Am J Emerg Med] Journal article | | Title | Management of femoral fracture in a patient with essential thrombocythemia treated with plateletpheresis and intramedullary rod fixation, followed by hydroxyurea: a case report. | | Author(s) | Edlich RF, Long WB, Cochran AA, Kelley AR, Woode DR, Greene JA, Takahashi GW | | Institution | Plastic Surgery, Biomedical Engineering, and Emergency Medicine, University of Virginia Health Systems, Charlottesville, VA, USA. richardedlichmd@gmail.com | | Source | Am J Emerg Med 2008 Jun; 26(5):636.e1-3. | | MeSH | Aged
Comorbidity
Emergency Medical Services
Femoral Fractures
Fracture Fixation, Intramedullary
Humans
Hydroxyurea
Janus Kinase 2
Male
Mutation
Nucleic Acid Synthesis Inhibitors
Platelet Count
Plateletpheresis
Thrombocythemia, Hemorrhagic
| | Abstract | We describe the management of a patient with a femoral fracture who had asymptomatic essential thrombocythemia. When the diagnosis of essential thrombocythemia was made, the patient was treated with plateletpheresis to reduce the platelet count before intramedullary rod fixation of his fracture. His postoperative management included the examination of his peripheral blood as well as bone marrow, which confirmed that the cause of his elevated platelet count was due to JAK2 V617F mutation that is treated by hydroxyurea and aspirin after being discharged from the hospital. | | Language | eng | | Pub Type(s) | Case Reports
Journal Article
| | PubMed ID | 18534315 |
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