| Title | A DNA vaccine for the prevention of Ebola virus infection. | | Author(s) | Dery M, Bausch DG | | Institution | Tulane University Health Sciences Center, Department of Medicine, Infectious Diseases Section, 1430 Tulane Ave SL-87, New Orleans, LA 70112-2699, USA. Email: madery@tulane.edu. | | Source | Curr Opin Mol Ther 2008 Jun; 10(3):285-93. | | Abstract | The NIH and Vical Inc are developing an intramuscular needle-free DNA vaccine containing plasmids encoding the envelope glycoprotein of Ebola virus (EBOV) from the Sudan and Zaire strains, and the nucleoprotein of EBOV Zaire strain. A phase I clinical trial demonstrated a good safety profile, with most adverse events limited to the site of injection and largely attributable to the delivery. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18535936 |
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