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Synthesis of some new quinazolin-4-one derivatives and evaluation of their antimicrobial and antiinflammatory effects. Acta poloniae pharmaceutica [Acta Pol Pharm] Journal article

 
Fathalla OA, Kassem EM, Ibrahem NM, Kamel MM 
Synthesis of some new quinazolin-4-one derivatives and evaluation of their antimicrobial and antiinflammatory effects. [Journal Article]
Acta Pol Pharm 2008 Jan-Feb; 65(1):11-20.


In this work, it was of interest to synthesize new series of some 2-[(E)-2-furan-2-yl-vinyl]-quinazolin-4(3H)-ones incorporated into pyrazoline, isoxazoline, pyrimidine or pyrimidine-thione ring systems at position-3 of the quinazoline ring. The antimicrobial activity and antiinflammatory effect of some of these compounds were studied.



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