| Title | Pharmacotherapy for patients with fibromyalgia. | | Author(s) | Clauw DJ | | Institution | Division of Rheumatology, Department of Internal Medicine, and Michigan Institute for Clinical and Health Research, University of Michigan Medical School, Ann Arbor, USA. dclauw@umich.edu | | Source | J Clin Psychiatry 2008.:25-9. | | MeSH | Aged
Analgesics, Opioid
Anti-Anxiety Agents
Antidepressive Agents, Tricyclic
Cognitive Therapy
Exercise
Female
Fibromyalgia
Humans
Serotonin Uptake Inhibitors
Tramadol
| | Abstract | Fibromyalgia is a common and disabling syndrome. Despite research detailing the efficacy of a variety of medicinal treatments, most notably, tricyclic antidepressants, serotonin-norepinephrine re-uptake inhibitors, and alpha(2)delta ligands, there is still widespread, routine use of agents that are mostly ineffective in treating the central nature of fibromyalgic pain. This article discusses pharmacotherapeutic options for fibromyalgia, including those with high-level evidence for efficacy, moderate-level evidence, and little or no evidence for efficacy. The importance of an integrated treatment approach that includes pharmacotherapy and at least one, but preferably more, of the most effective nonmedicinal treatment options available (e.g., education, aerobic exercise, and cognitive-behavioral therapy) is also discussed. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
Review
| | PubMed ID | 18537460 |
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