| Title | Transcatheter closure of perimembranous ventricular septal defect using a modified double-disk occluder. | | Author(s) | Qin Y, Chen J, Zhao X, Liao D, Mu R, Wang S, Wu H, Guo H | | Institution | Department of Cardiology, Changhai Hospital, Second Military Medical University, Shanghai, China. | | Source | Am J Cardiol 2008 Jun 15; 101(12):1781-6. | | Abstract | This multicenter study assessed the efficacy and safety of transcatheter closure of perimembranous ventricular septal defect (VSD) using a modified double-disk occluder. In 5 different centers in China, 412 patients with VSD, including 202 men and 210 women, underwent attempted transcatheter closure. The age range was 3 to 65 years (mean 16.4+/-9.1). The diameter of defect was 3 to 15 mm by transthoracic echocardiography and 3 to 18 mm by left ventriculography. The ratio of pulmonary to systemic flow varied from 1.6 to 2.3 (1.9+/-0.4). The device diameter was 4 to 20 mm (7.09+/-3.60). The ventricular septal rim below the aortic valve was 0 to 5 mm. The immediate success rate was 96.6%; 6 cases had third degree atrioventricular block and recovered within 3 weeks. None needed a permanent pacemaker. Dislodgement of the device occurred in 3 patients but the device was recaptured and redeployed in 2 cases. During the follow-up period of 2 years, there was no evidence of residual shunt and device-related complications. In conclusion, transcatheter closure of VSD is safe and effective in most selected patients; the mid-term prognosis of patients with transcatheter closure is good. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18549859 |
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