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Chemoembolization of hepatic metastases from ocular melanoma: assessment of response with contrast-enhanced and diffusion-weighted MRI. AJR. American journal of roentgenology [AJR Am J Roentgenol] Journal article

 
Buijs M, Vossen JA, Hong K, Georgiades CS, Geschwind JF, Kamel IR 
Chemoembolization of hepatic metastases from ocular melanoma: assessment of response with contrast-enhanced and diffusion-weighted MRI. [Journal Article]
AJR Am J Roentgenol 2008 Jul; 191(1):285-9.


OBJECTIVE: The purpose of this study was to assess the utility of assessment of tumor size and enhancement with diffusion-weighted and conventional MRI in the evaluation of response to transarterial chemoembolization therapy for metastatic ocular melanoma.
CONCLUSION: In patients with ocular melanoma and liver metastasis treated with transarterial chemoembolization, functional MRI showed significant changes in the lesions. These changes included a decrease in tumor enhancement and an increase in the apparent diffusion coefficient of the tumor, suggesting increasing tumor necrosis and cell death.



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