| Title | Chemoembolization of hepatic metastases from ocular melanoma: assessment of response with contrast-enhanced and diffusion-weighted MRI. | | Author(s) | Buijs M, Vossen JA, Hong K, Georgiades CS, Geschwind JF, Kamel IR | | Institution | Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins Hospital, 601 N Caroline St., Rm. 3235A, Baltimore, MD 21287, USA. | | Source | AJR Am J Roentgenol 2008 Jul; 191(1):285-9. | | MeSH | Aged
Chemoembolization, Therapeutic
Contrast Media
Diffusion Magnetic Resonance Imaging
Eye Neoplasms
Female
Gadolinium DTPA
Humans
Liver Neoplasms
Male
Melanoma
Outcome Assessment (Health Care)
Prognosis
Treatment Outcome
| | Abstract | OBJECTIVE: The purpose of this study was to assess the utility of assessment of tumor size and enhancement with diffusion-weighted and conventional MRI in the evaluation of response to transarterial chemoembolization therapy for metastatic ocular melanoma.
CONCLUSION: In patients with ocular melanoma and liver metastasis treated with transarterial chemoembolization, functional MRI showed significant changes in the lesions. These changes included a decrease in tumor enhancement and an increase in the apparent diffusion coefficient of the tumor, suggesting increasing tumor necrosis and cell death. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 18562760 |
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