Optical coherence tomography imaging of the inner ear: a feasibility study with implications for cochlear implantation. The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] Journal article

Title	Optical coherence tomography imaging of the inner ear: a feasibility study with implications for cochlear implantation.
Author(s)	Lin J, Staecker H, Jafri MS
Institution	Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, USA.
Source	Ann Otol Rhinol Laryngol 2008 May; 117(5):341-6.
MeSH	Animals Cadaver Cochlear Implants Disease Models, Animal Ear, Inner Equipment Design Feasibility Studies Follow-Up Studies Hearing Loss Humans Mice Mice, Inbred CBA Reproducibility of Results Tomography, Optical Coherence
Abstract	Cochlear implantation is now being performed in ears with residual hearing. Those implant recipients who keep residual hearing may benefit from improved pitch resolution through both electrical and acoustic hearing. Preservation of cochlear function after implantation is a challenging task for the surgeon. Current topics of hearing preservation research include electrode design and surgical technique. To maintain hearing, surgeons strive to create a cochleostomy and place the electrode in a minimally traumatic fashion. In this study, we examine a novel catheter-based real-time imaging modality with 10- to 15-microm resolution, optical coherence tomography (OCT), on the inner ear. We demonstrate the capability of OCT to allow visualization of inner ear structures through bone in live mice. We additionally used OCT to image the inner ear in a human temporal bone. Optical coherence tomography was able to delineate soft tissue structures within the cochlea and may be useful as an adjunct to cochlear implantation. Other potential otologic applications of OCT are discussed.
Language	eng
Pub Type(s)	Journal Article Research Support, U.S. Gov't, Non-P.H.S.
PubMed ID	18564530

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