El Fassi D, Nielsen CH, Hegedüs L
[B-lymphocyte depleting and other biological treatment options for Graves' ophthalmopathy] [English Abstract, Journal Article]
Ugeskr Laeger 2008 Jun 9; 170(24):2128-30.
The current medical treatment options for Graves' ophthalmopathy (GO) are unsatisfactory. Recent treatment of GO patients with the B-lymphocyte depleting monoclonal antibody rituximab or with the anti-tumor necrosis factor-alpha agents etanercept and infliximab has shown promising results. We discuss the use of these and other biological agents targeting B lymphocytes, T-lymphocyte interaction with antigen-presenting cells, or cytokines in the future treatment of GO.
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