Impact of antiretroviral therapy on chemokine (C-C motif) receptor 5 expression in HIV patients followed for over 2 years. AIDS (London, England) [AIDS] Journal article | | Title | Impact of antiretroviral therapy on chemokine (C-C motif) receptor 5 expression in HIV patients followed for over 2 years. | | Author(s) | Briz V, Poveda E, López M, González Mdel M, Soriano V, Benito JM | | Institution | Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain. | | Source | AIDS 2008 Jul 11; 22(11):1371-4. | | Abstract | Suppression of HIV replication using highly active antiretroviral therapy (HAART) might influence chemokine (C-C motif) receptor 5 expression on infected cells and therefore modulate the activity of chemokine (C-C motif) receptor 5 antagonists. Chemokine (C-C motif) receptor 5 expression was examined longitudinally in 26 HIV-infected adults who initiated HAART. Long-term suppression of plasma HIV-RNA did not significantly influence chemokine (C-C motif) receptor 5 expression on T lymphocytes. Therefore, the activity of chemokine (C-C motif) receptor 5 antagonists should not differ before and following HIV suppression on HAART. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
| | PubMed ID | 18580618 |
|
|
| |
Advertise on this site.
| | |
|
