| Title | Colloidal carriers for the enhanced delivery through the skin. | | Author(s) | Cosco D, Celia C, Cilurzo F, Trapasso E, Paolino D | | Institution | 1University 'Magna Graecia' of Catanzaro, Campus Universitario - Building of Biosciences, Department of Pharmacobiological Sciences, Faculty of Pharmacy, Viale Europa, I-88100 Germaneto (CZ), Italy, 2Faculty of Medicine University 'Magna Graecia' of Catanzaro, Campus Universitario - Building of Biosciences, Department of Experimental and Clinical Medicine, Viale Europa, I-88100 Germaneto (CZ), Italy +39 0961 3694118 ; +39 0961 3694237 ; paolino@unicz.it. | | Source | Expert Opin Drug Deliv 2008 Jul; 5(7):737-755. | | Abstract | Background: The skin is the largest organ of our body and acts as a protective barrier with sensory and immunological functions. Its peculiar structure influences the passage of bioactives and only its modulation can facilitate the drug dermal/transdermal diffusion. In the past few years research in this field has assured better use of this application area.
Methods: One of the most promising approaches is the use of drug delivery devices; this review explains the state of the art of drug transport through the skin by means of vesicular (classic liposomes, Transfersomes, niosomes and ethosomes) and particulate systems. Results/conclusion: Colloidal drug delivery systems are important in the field of drug delivery systems as their different characteristics make them suitable for various purposes. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18590459 |
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