| Abstract | One of the most relevant investigations on cancer during the past 25 years in the scientific community is the increasing knowledge about HPV infection and its ethiologic relationship with cervical cancer, even the most with persistent infection of specific genotypes of this virus. Worldwide, a woman dies from cervical cancer every 2 minutes. There are two potential concerns associated with vaccination: In the past we developed a secondary prevention programme, potentially based on screening. Now, vaccines have demonstrated a high grade of efficacy and security, specially when administered to pre-adolescents, and there will be a lower prevalence of the disease, as has already been shown in ongoing and completed trials, and secondary, avoidance of unnecessary diagnostic procedures and costs. In this evaluation we look forward to results on long-term vaccine efficacy and the possibility to make a pooled analysis on vaccine efficacy in preventing cervical cancer. Although some of us may not see it, we undoubtedly believe that we are close to the begining of the end of cervical cancer. |
