A Non-randomized, Open Study with Aripiprazole and Ziprasidone for the Treatment of Aggressive Behavior in Youth in a Community Clinic. Community mental health journal [Community Ment Health J] Journal article | | Title | A Non-randomized, Open Study with Aripiprazole and Ziprasidone for the Treatment of Aggressive Behavior in Youth in a Community Clinic. | | Author(s) | Bastiaens L | | Institution | Family Services of Western Pennsylvania, University of Pittsburgh, 33 Sunnyhill Drive, Pittsburgh, PA, 15228, USA, Bastiaensl@aol.com. | | Source | Community Ment Health J 2008 Jul 3. | | Abstract | Forty-six patients (36 male, mean age 11.9 +/- 2.6) with a variety of diagnoses and with significant aggressive behavior were treated in an open, non-randomized fashion with Aripiprazole or Ziprasidone. Patients were diagnosed with the Mini International Neuropsychiatric Interview and the Child/Adolescent Symptom Inventory. The primary outcome measure was the Overt Aggression Scale (OAS). After 2 months, 34 patients were still in treatment. The average improvement of the OAS in these 34 patients was 63%. Clinical Global Impression-Improvement Scale was 2.1 +/- 1.2. Neither at baseline, nor at 2 months, were there any statistically significant differences between the Aripiprazole and Ziprasidone groups. Sedation was the most common side effect. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18597173 |
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