The value of patch testing patients with a scattered generalized distribution of dermatitis: Retrospective cross-sectional analyses of North American Contact Dermatitis Group data, 2001 to 2004. Journal of the American Academy of Dermatology [J Am Acad Dermatol] Journal article | | Title | The value of patch testing patients with a scattered generalized distribution of dermatitis: Retrospective cross-sectional analyses of North American Contact Dermatitis Group data, 2001 to 2004. | | Author(s) | Zug KA, Rietschel RL, Warshaw EM, Belsito DV, Taylor JS, Maibach HI, Toby Mathias CG, Fowler JF, Marks JG, Deleo VA, Pratt MD, Sasseville D, Storrs FJ | | Institution | Section of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. | | Source | J Am Acad Dermatol 2008 Jun 30. | | Abstract | BACKGROUND: A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor.
OBJECTIVE: We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for patch testing with SGD.
METHODS: We conducted retrospective cross-sectional analysis of North American Contact Dermatitis Group 2001 to 2004 data. Patients with SGD were compared with patients without SGD.
RESULTS: Of 10,061 patients, 14.9% (n = 1497) had only a SGD. Men and patients with a history of atopic eczema were more likely to have dermatitis in a SGD (P < .001). Preservatives, fragrances, propylene glycol, cocamidopropyl betaine, ethyleneurea melamine formaldehyde, tixocortol pivalate, and budesonide were among the more frequently relevant positive allergens. Top allergen sources included cosmetics/beauty preparations/skin and health care products, clothing, and topical corticoids.
LIMITATIONS: This was a retrospective analysis of patch-tested patients with SGD suspected to have allergy.
CONCLUSIONS: A total of 49% of patients with SGD had at least one relevant positive allergen, thus demonstrating the benefit of patch testing these patients. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18597890 |
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