| Title | Human hydatid disease in Peru is basically restricted to Echinococcus granulosus genotype G1. | | Author(s) | Santivañez SJ, Gutierrez AM, Rosenzvit MC, Muzulin PM, Rodriguez ML, Vasquez JC, Rodriguez S, Gonzalez AE, Gilman RH, Garcia HH, Cysticercosis Working Group in Peru | | Institution | Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru. | | Source | Am J Trop Med Hyg 2008 Jul; 79(1):89-92. | | MeSH | Animals
Camels
DNA, Helminth
DNA, Mitochondrial
Dogs
Echinococcosis
Echinococcus granulosus
Electron Transport Complex IV
Genotype
Humans
Peru
Polymerase Chain Reaction
Sheep
Sheep Diseases
Zoonoses
| | Abstract | A molecular PCR study using DNA from 21 hydatid cysts was performed to determine which strain type is responsible for human infection in Peru. The mitochondrial cytochrome c oxidase subunit 1 (CO1) gene was amplified in 20 out of 21 samples, revealing that all but 1 sample (19/20, 95%) belonged to the common sheep strain (G1). The remaining samples belonged to the camel strain (G6). The G1 genotype was most frequently found in human cases of cystic hydatid disease (CHD) in Peru. Local control measures should focus primarily on decreasing dog and sheep infection rather than intermediate reservoirs. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
| | PubMed ID | 18606769 |
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