| Title | The effect of high-dose topical corticosteroid therapy on prevention of recurrent nasal polyps after revision endoscopic sinus surgery. |
| Author(s) | Kang IG, Yoon BK, Jung JH, Cha HE, Kim ST |
| Institution | Department of Otolaryngology-Head and Neck Surgery, Gachon, University Gil Medical Center, Incheon, Korea. |
| Source | Am J Rhinol 2008 Sep-Oct; 22(5):497-501. |
| MeSH | Administration, Topical
Adult
Aged
Dose-Response Relationship, Drug
Endoscopy
Female
Follow-Up Studies
Glucocorticoids
Humans
Male
Middle Aged
Nasal Polyps
Otorhinolaryngologic Surgical Procedures
Postoperative Care
Recurrence
Retrospective Studies
Treatment Outcome
Triamcinolone Acetonide
|
| Abstract | BACKGROUND: Topical corticosteroid spray is widely used after endoscopic sinus surgery (ESS) to reduce the recurrence of polyposis. However, it has not always shown satisfactory results in clinical practice. We compared the effects of topical spray and high-dose topical steroid gauze packing on the prevention of recurrent nasal polyps after ESS.
METHODS: We selected 32 patients with recurrent nasal polyps after ESS. In group 1, 18 patients were treated with topical steroid spray and in group 2, 14 patients were treated with triamcinolone acetonide-soaked (40 mg) gauze packing once a week for 2 months after revision ESS. We observed the recurrence of polyps between the two groups for 12 months.
RESULTS: Polyps recurred in 8 of 18 patients in group 1 compared with 1 of 14 patients in group 2 (p = 0.044).
CONCLUSION: High-dose topical corticosteroid therapy may be more effective than low-dose topical therapy in preventing recurrent nasal polyps. |
| Language | eng |
| Pub Type(s) | Comparative Study
Journal Article
|
| PubMed ID | 18684343 |
