Bracke A, Van Marck E, Lambert J
Acute generalized exanthematous pustulosis after pemetrexed, and recurrence after re-introduction. [JOURNAL ARTICLE]
Clin Exp Dermatol 2008 Aug 9.
Acute generalized exanthematous pustulosis (AGEP) is a rare cutaneous reaction, which in most cases, is related to medication. Pemetrexed is an antifolate drug, approved for treatment of metastatic non-small-cell lung cancer (NSCLC) and malignant pleural mesothelioma (MPM). We present a case of AGEP caused by pemetrexed, and a recurrence of this eruption after re-introduction of pemetrexed despite use of corticosteroids.
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