| Title | Lichen planus pemphigoides associated with Chinese herbs. | | Author(s) | Xu HH, Xiao T, He CD, Jin GY, Wang YK, Gao XH, Chen HD | | Institution | Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, China. | | Source | Clin Exp Dermatol 2008 Aug 9. | | Abstract | We report a 62-year-old Chinese woman with a 2-year history of lichen planus presenting with extensive violaceous maculopapules and plaques 1 week after taking an oral preparation of Chinese herbs. The patient developed vesiculobullous skin lesions 7 weeks later. Histopathological examination showed subepidermal blisters and adjacent bandlike lymphocytic infiltration. Direct immunofluorescence revealed linear deposits of IgG and C3 along the basement membrane zone. Indirect immunofluorescence showed IgG antibody deposition along the epidermal side of salt-split human skin. Circulating anti-bullous pemphigoid 180 antibodies were detected by ELISA. Lichen planus pemphigoides (LPP) was diagnosed. To our knowledge, this is the first report of LPP associated with oral Chinese herbs. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 18699839 |
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