Detection of HLA-antibodies prior to renal transplantation: prospects and limitations of new assays. Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology [Swiss Med Wkly] Journal article | | Title | Detection of HLA-antibodies prior to renal transplantation: prospects and limitations of new assays. | | Author(s) | Amico P, Hönger G, Mayr M, Schaub S | | Institution | Clinic for Transplantation Immunology and Nephrology, University Hospital Basel, Basel, Switzerland. | | Source | Swiss Med Wkly 2008 Aug 23; 138(33-34):472-6. | | MeSH | Flow Cytometry
Graft Rejection
HLA Antigens
Humans
Kidney Transplantation
| | Abstract | Donor-specific HLA antibodies are responsible for most early renal allograft rejections and allograft losses. Therefore, detection of HLA antibodies prior to transplantation is an important step in the evaluation of renal allograft recipients. In this mini-review we will describe recent advances in the techniques used to detect donor-specific HLA antibodies with emphasis on their potential application for patient management and their current limitations. | | Language | eng | | Pub Type(s) | Journal Article
Research Support, Non-U.S. Gov't
Review
| | PubMed ID | 18726732 |
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