| Title | Management of asymptomatic severe aortic stenosis. | | Author(s) | Dal-Bianco JP, Khandheria BK, Mookadam F, Gentile F, Sengupta PP | | Institution | Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA. | | Source | J Am Coll Cardiol 2008 Oct 14; 52(16):1279-92. | | MeSH | Aged
Angioplasty, Balloon
Aortic Valve Stenosis
Echocardiography, Doppler
Electrocardiography
Exercise Test
Female
Heart Valve Prosthesis Implantation
Humans
Magnetic Resonance Imaging
Male
Postoperative Complications
Predictive Value of Tests
Prognosis
Randomized Controlled Trials as Topic
Risk Assessment
Severity of Illness Index
Stroke Volume
Survival Analysis
| | Abstract | Patients with symptomatic severe aortic stenosis (AS) benefit from aortic valve replacement (AVR). Management of severe AS in the absence of symptoms is, however, controversial and often challenging. Unselected premature AVR carries the risks of cardiac surgery; delayed AVR due to unrecognized symptoms can result in a dismal outcome. Echocardiography is the standard tool to evaluate and follow patients with AS. Nevertheless, most of the current echocardiographic parameters have limitations in predicting symptom onset and clinical outcome. The same applies to clinical parameters, exercise stress testing, and other imaging modalities used in AS evaluation and serial follow-up. Predictors of outcome could, however, help to identify asymptomatic patients who would benefit from expedited AVR with the goal to reduce mortality. This review will discuss the most relevant clinical studies and guidelines on management of asymptomatic severe AS, with an emphasis on providing concise information for identifying patients at high risk. | | Language | eng | | Pub Type(s) | Journal Article
Review
| | PubMed ID | 18929238 |
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