Macdiarmid S, Sandage BW, Malhotra BK
The effects of reformulation: improved therapeutic index. [Journal Article]
Curr Urol Rep 2008 Nov; 9(6):465-71.
Antimuscarinic agents are the treatment of choice for overactive bladder syndrome. Due to the development of novel delivery systems, extended-release formulations of oxybutynin, tolterodine, and trospium chloride are now available. In addition to the convenience of once-daily dosing, the new formulations of these commonly prescribed agents have improved their therapeutic index, striking a better balance between efficacy and tolerability.
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