Golla S, Horkan C, Dogaru G, Teske TE, Christopher K
Rapid encephalopathy associated with anti-D immune globulin treatment for idiopathic thrombocytopenic purpura. [Case Reports, Journal Article]
Acta Haematol 2008; 120(2):100-3.
Rho (D) immune globulin intravenous (IV RhIG, WinRho SDF) has been shown to be a safe treatment for idiopathic thrombocytopenic purpura. Common side effects of IV RhIG include mild hemolysis, febrile reaction and headache. Significant hemolysis with renal impairment is infrequently noted. A single case of irreversible encephalopathy following IV RhIG has been reported. We report a second case of encephalopathy following an infusion of IV RhIG for treatment of idiopathic thrombocytopenic purpura.
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