| Title | Rapid encephalopathy associated with anti-D immune globulin treatment for idiopathic thrombocytopenic purpura. | | Author(s) | Golla S, Horkan C, Dogaru G, Teske TE, Christopher K | | Institution | Department of Medicine, MetroWest Medical Center, Framingham, Mass., USA. | | Source | Acta Haematol 2008; 120(2):100-3. | | MeSH | Aged, 80 and over Cerebral Hemorrhage Fatal Outcome Female Humans Neurotoxicity Syndromes Purpura, Thrombocytopenic, Idiopathic Rho(D) Immune Globulin
| | Abstract | Rho (D) immune globulin intravenous (IV RhIG, WinRho SDF) has been shown to be a safe treatment for idiopathic thrombocytopenic purpura. Common side effects of IV RhIG include mild hemolysis, febrile reaction and headache. Significant hemolysis with renal impairment is infrequently noted. A single case of irreversible encephalopathy following IV RhIG has been reported. We report a second case of encephalopathy following an infusion of IV RhIG for treatment of idiopathic thrombocytopenic purpura. | | Language | eng | | Pub Type(s) | Case Reports Journal Article
| | PubMed ID | 18957844 |
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