Creel AM, Crawford D, Prabhakaran P Anaphylaxis and Superior Vena Cava Thrombus in a Pediatric Patient With Acute Lymphoblastic Leukemia. [JOURNAL ARTICLE] Pediatr Emerg Care 2008 Nov; 24(11):771-773.
Pediatric patients with malignancies are at significant risk for complications from their underlying condition and medical therapy. Emergency medicine physicians must be quick to suspect life-threatening events, which can present insidiously. We describe a case of anaphylaxis and superior vena cava syndrome in an 18-year-old female patient after polyethylene glycol-conjugated asparaginase chemotherapy for acute lymphoblastic leukemia. Pertinent literature surrounding risk factors, diagnosis, and treatment is also reviewed.
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