Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. The Mount Sinai journal of medicine, New York [Mt Sinai J Med] Journal article | | Title | Insulin strategies for managing inpatient and outpatient hyperglycemia and diabetes. | | Author(s) | Moghissi ES, FACE | | Institution | Department of Medicine, University of California at Los Angeles, Los Angeles, CA. | | Source | Mt Sinai J Med 2008 Nov 19; 75(6):558-566. | | Abstract | Optimal fasting and postprandial glycemic control are essential to limiting microvascular and macrovascular complications associated with diabetes. Recently, stringent control of hyperglycemia in critically ill hospitalized patients with diabetes or acute hyperglycemia has been shown to reduce the risk of morbidity and mortality. This article reviews effective strategies for insulin initiation, titration, and intensification in inpatient and outpatient settings and discusses current treatment strategies when patients are being transitioned from the intensive care unit to general wards and discharged. The development of insulin analogs and premixed insulin analogs has created new options for treating inpatients and outpatients. The more physiologic time-action profiles, improved insulin delivery systems, and standardized protocols for subcutaneous insulin administration and intravenous insulin infusion have improved the safety and convenience of insulin therapy. Mt Sinai J Med 75:558-566, (c) 2008 Mount Sinai School of Medicine. | | Language | ENG | | Pub Type(s) | JOURNAL ARTICLE
| | PubMed ID | 19021195 |
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