Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases. Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] Journal article

Title	Oral and parenteral therapeutic options for outpatient urinary infections caused by enterobacteriaceae producing CTX-M extended-spectrum beta-lactamases.
Author(s)	Prakash V, Lewis JS, Herrera ML, Wickes BL, Jorgensen JH
Institution	San Antonio Military Medical Center, Infectious Disease Service, San Antonio, Texas 78234, USA.
Source	Antimicrob Agents Chemother 2009 Mar; 53(3):1278-80.
MeSH	Administration, Oral Amoxicillin-Potassium Clavulanate Combination Anti-Bacterial Agents Cephalosporins Cross Infection Enterobacteriaceae Escherichia coli Fosfomycin Humans Infusions, Parenteral Microbial Sensitivity Tests Outpatients Urinary Tract Infections beta-Lactamases beta-Lactams
Abstract	Effective therapeutic options are needed for community-onset urinary tract infections due to Escherichia coli strains that produce CTX-M extended-spectrum beta-lactamases. We examined 46 urinary isolates producing CTX-M against several oral or long-acting parenteral antimicrobial agents. Approximately 90% were susceptible to fosfomycin and to a combination of cefdinir plus amoxicillin-clavulanate. All were susceptible to ertapenem.
Language	eng
Pub Type(s)	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.
PubMed ID	19124661

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