| Title | Hemophagocytic lymphohistiocytosis onset during induction therapy for precursor B-cell acute lymphoblastic leukemia. | | Author(s) | Breakey VR, Abdelhaleem M, Weitzman S, Abla O | | Institution | Division of Pediatric Haematology and Oncology, Department of Paediatric Medicine, Hospital for Sick Children, Toronto, Canada. vsventzouris@yahoo.com | | Source | J Pediatr Hematol Oncol 2008 Dec; 30(12):956-8. | | Abstract | We report the clinical course of a child with precursor B-cell acute lymphoblastic leukemia who developed fever, hepatosplenomegaly, and refractory thrombocytopenia after initiation of chemotherapy. Bone marrow aspiration on Day 8 of induction showed new onset of hemophagocytosis and he met clinical, laboratory, and histopathologic criteria for hemophagocytic lymphohistiocytosis. His symptoms improved significantly after an increased dosage of steroids. | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19131791 |
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