Rothman RB, Hendricks EJ
Phentermine cardiovascular safety In response to Yosefy C, Berman M, Beeri R. Cusp tear in bicuspid aortic valve possibly caused by phentermine. International journal of cardiology 2006;106:262-3. [JOURNAL ARTICLE]
Int J Cardiol 2009 Feb 1.
A letter to the editor "Cusp tear in bicuspid valve possibly caused by phentermine" published in volume 106 (2006) stated "Phentermine is known to cause valvular disease with prolonged use." There is no evidence that phentermine causes valvulopathy. Phentermine is the most widely used anti-obesity drug. In view of the serious cardiovascular risks associated with obesity, it is important to clarify that phentermine is a safe and effective anti-obesity medication.
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