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Effect of epsilon-aminocaproyl-S-benzyl-L-cysteine on the activity of plasminogen activators. Acta poloniae pharmaceutica [Acta Pol Pharm] Journal article

 
Bruzgo I, Midura-Nowaczek K, Kaczyńska J, Krajewska D 
Effect of epsilon-aminocaproyl-S-benzyl-L-cysteine on the activity of plasminogen activators. [Journal Article]
Acta Pol Pharm 2009 Jan-Feb; 66(1):37-40.


The effect of epsilon-aminocaproyl-S-benzyl-L-cysteine on the activation of plasminogen by t-PA. streptokinase and urokinase has been examined using fibrinolytic method. The obtained results have been compared with the obtained results for epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexanecarboxylic acid. The inhibition of the plasminogen activation determined with the use of epsilon-aminocaproyl-S-benzyl-L-cysteine was weaker than the inhibition determined by using antifibrinolytic aminoacids.



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