Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101. Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] Journal article

Title	Comparative in vitro susceptibilities of human mycoplasmas and ureaplasmas to a new investigational ketolide, CEM-101.
Author(s)	Waites KB, Crabb DM, Duffy LB
Institution	Department of Pathology, 619 19th Street South, WP 230, University of Alabama at Birmingham, Birmingham, AL 35249, USA. waiteskb@uab.edu
Source	Antimicrob Agents Chemother 2009 May; 53(5):2139-41.
MeSH	Anti-Bacterial Agents Drug Resistance, Bacterial Humans Ketolides Microbial Sensitivity Tests Mycoplasma Mycoplasma Infections Mycoplasma fermentans Mycoplasma genitalium Mycoplasma pneumoniae Ureaplasma Ureaplasma Infections
Abstract	MICs were determined for an investigational ketolide, CEM-101, and azithromycin, telithromycin, doxycycline, levofloxacin, clindamycin, and linezolid against 36 Mycoplasma pneumoniae, 5 Mycoplasma genitalium, 13 Mycoplasma hominis, 15 Mycoplasma fermentans, and 20 Ureaplasma isolates. All isolates, including two macrolide-resistant M. pneumoniae isolates, were inhibited by CEM-101 at < or = 0.5 microg/ml, making CEM-101 the most potent compound tested.
Language	eng
Pub Type(s)	Comparative Study Journal Article Research Support, Non-U.S. Gov't
PubMed ID	19258276

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