| Title | Paediatric painful bladder syndrome/interstitial cystitis: diagnosis and treatment. | | Author(s) | Sea J, Teichman JM | | Institution | Division of Urology, Providence Healthcare and Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada. | | Source | Drugs 2009; 69(3):279-96. | | Abstract | To describe the pathophysiology, diagnosis and controversies surrounding the diagnosis and pharmacological treatments of painful bladder syndrome/interstitial cystitis (PBS/IC) in children, we reviewed adult and paediatric literature pertaining to PBS/IC. Paediatric PBS/IC presents similarly to adult PBS/IC. The diagnosis is made by exclusion. Paediatric PBS/IC patients complain most commonly of urinary frequency, and abdominal pain occurs in up to 88% of affected children. Enuresis may also be a presenting complaint. Urinalysis and urine cultures are unremarkable. Management of paediatric PBS/IC is similar to that of adult PBS/IC, and non-surgical management includes dietary, lifestyle and pharmacological therapy. Pharmacological options include pentosan polysulfate, amitriptyline, hydroxyzine, cimetidine or intravesical therapies (dimethyl sulfoxide or 'therapeutic solution'). | | Language | eng | | Pub Type(s) | Journal Article
| | PubMed ID | 19275272 |
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